eyecro data to be presented at ARVO 2016 in Seattle


The promising clinical results obtained for ocular gene therapy in recent years have paved the way for gene supplementation to treat recessively inherited forms of retinal degeneration. We used spliceosome-mediated RNA trans-splicing as a strategy for repairing the transcript of the rhodopsin gene, the gene most frequently mutated in autosomal dominant retinitis pigmentosa (RP). Retinitis…
Inflammation is one of the main reasons why people with diabetes experience heart attacks, strokes, kidney problems and other, related complications. Now, in a surprise finding, researchers at Washington University School of Medicine in St. Louis have identified a possible trigger of chronic inflammation. Through a series of experiments in the animals and in cell…
Hiding in the back of your eye are stem cells from the central nervous system, scientists have discovered. The stem cells in question were found in a special layer of cells in the eye called the retinal pigment epithelium, or RPE. Just one cell thick, the layer lies underneath the retina, the eye’s light sensor….
The University of Melbourne–lead team of researchers have grown corneal cells on a layer of film that can be implanted in the eye to help the cornea heal itself. They have successfully restored vision in animal trials and are aiming to move to human trials next year. “The hydrogel film we have developed allows us to…
Having diabetic retinopathy and/or microalbuminuria predicted a much higher rate of annual decline in glomerular filtration rate (GFR) in a new study of patients with type 2 diabetes living in Japan. Diabetic retinopathy is a known risk factor for microalbuminuria, and microalbuminuria is a risk factor for macroalbuminuria, but to date it has been unclear…
A research team led by scientists at Beth Israel Deaconess Medical Center (BIDMC) and the University of New Mexico School of Medicine has identified a small molecule that treats animal models of aged macular degeneration (AMD) and retinopathy of prematurity (ROP) by preventing the overgrowth of blood vessels that are characteristic of these two retinal…