“Toward enhancing ethical practices in scientific research, EyeCRO has joined several industry-leading companies to sign the “Marseille Declaration”, the first joint pharmaceutical industry declaration on animal housing and use.” Click here to read the full press release
Regenerative medicine company jCyte and the Sue & Bill Gross Stem Cell Research Center at the University of California, Irvine report that their investigational therapy for retinitis pigmentosa (RP) has demonstrated a favorable safety and tolerability profile in an ongoing Phase I/II clinical trial. The cell-based approach taken is intended to rescue sick and dying…
Rafal Farjo, PhD, COO of eyecro, told Outsourcing-pharma.com that the “demand for ophthalmology studies is increasing. Many research scientists are uncovering new mechanisms and targets for ophthalmic disease, it is also becoming apparent that there is pathology in common with many other clinical indications. eyecro specializes in ophthalmic studies of preclinical efficacy, pharmacokinetics, toxicology, and…
“NEW YORK (Reuters Health) – In patients with unilateral neovascular age-related macular degeneration (AMD), certain drusen features are associated with conversion to neovascular AMD in the fellow eye, according to a secondary analysis of data from a clinical trial. Dr. Joelle A. Hallak of the University of Illinois at Chicago and colleagues used machine learning…
Retinol-Binding Protein 4 Induces Inflammation in Human Endothelial Cells by a NADPH Oxidase- and Nuclear Factor Kappa B-dependent and Retinol-Independent Mechanism Krysten M. Farjoa,#, Rafal A. Farjob, Stacey Halseya, Gennadiy Moiseyeva and Jian-xing Maa aDepartment of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma beyecro LLC, Oklahoma City, Oklahoma ABSTRACT Serum retinol-binding protein…
Retinal detachment can occur as a result of either blunt trauma or as a side effect of a variety of ophthalmic diseases, including diabetic retinopathy, ocular tumors, and age-related macular degeneration. There is a significant increase in the immune system’s ‘alternative complement pathway’ following retinal detachment, researchers report, adding that this pathway facilitated early photoreceptor…
Brainsway Ltd. has announced interim results from an animal study being conducted at the Sheba Medical Center to explore the effects of the company’s transcranial magnetic stimulation device on age-related macular degeneration. A short-lasting improvement in the retina’s response to light was observed following this stage of the study, with the rats who received the magnetic…