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https://eyecro.com

  • AboutUs_Normal-24 The EyeCRO Approach
    • About Us
    • Careers
    • Location
    • Partners
  • MiDrops MiDROPS™
  • InVivo Models
    • Allergic Conjunctivitis
    • Corneal Sensitivity
    • Corneal Wound Healing
    • Diabetic Keratopathy
    • DL-AAA Retinal Leakage
    • Dry Eye Disease
    • Endotoxin induced Uveitis
    • Experimental Autoimmune Uveitis
    • Geographic Atrophy
    • Inherited Retinal Degenerations
    • Ischemia Reperfusion Injury
    • Laser-induced Choroidal Neovascularization
    • Light Damaged
    • Mitochondrial Neuropathy
    • Optic Nerve Crush
    • Oxygen Induced Retinopathy
    • Retinal Detachment
    • Retinal Vein Occlusion
    • STZ-induced Diabetic Retinopathy
    • VEGF-induced permeability
  • InVitro Capabilities
    • A2E Quantification
    • Bioanalytical Detection
    • Biochemistry
    • Histology
    • Ophthalmic Imaging and Physiology
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Preclinical Ophthalmic Contract Research

Connor Hodde

EyeCRO scientists contribute to study published in Nature

April 21, 2020 //  by Connor Hodde

"Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision. The lab-made rods enabled blind mice to detect light after the cells were transplanted into the animals' eyes. The work, funded by the National Eye Institute (NEI), published April 15 in Nature." (Click here to read rest of article) …

Category: News

Is Treat-and-Extend Truly Effective for Diabetic Macular Edema?

September 11, 2019 //  by Connor Hodde

"Anti-vascular endothelial growth factor (anti-VEGF) medications have a proven track record in treating diabetic macular edema (DME). However, researchers continue to investigate whether these medications can be made more efficient and cost-effective." "Both the RETAIN[1] and REACT[2] studies showed that treat-and-extend regimens for ranibizumab were efficacious for DME. Further support was …

Category: News

New Age-Related Macular Degeneration Common in Untreated Fellow Eyes

July 24, 2019 //  by Connor Hodde

"NEW YORK (Reuters Health) - New age-related macular degeneration (AMD) develops in about a quarter of fellow eyes to those treated for neovascular AMD with intravitreal anti-VEGF agents, according to a post hoc analysis of the VIEW 1 and VIEW 2 studies." "The high risk for fellow eye conversion in patients with neovascular AMD in one eye highlights the need to explore prophylactic treatments …

Category: News

Double-Barreled Biologic for Diabetic Retinopathy Emerging

July 16, 2019 //  by Connor Hodde

CHICAGO — Investigators searching for new ways to manage diabetic macular edema are targeting pathways beyond vascular endothelial growth factor (VEGF). Phase 2 results from the BOULEVARD trial (NCT02699450), which is comparing faricimab, the first biologic to target both the Ang-2 and VEGF pathways, with ranibizumab, will be presented at the American Society of Retina Specialists (ASRS) 2019 …

Category: News

FLUID Study Rethinks Treat-and-Extend Protocols in Neovascular AMD

June 12, 2019 //  by Connor Hodde

"For patients with neovascular age-related macular degeneration (nAMD), a major cause of visual impairment worldwide,[1] the advent of anti–vascular endothelial growth factor (VEGF) intravitreal injections has been an undeniable breakthrough.  Anti-VEGF therapy allows for greater control of the exudative process, which can dramatically improve outcomes compared with observation alone." "Achieving …

Category: News

Brolucizumab as Good as Aflibercept for Neovascular AMD

June 4, 2019 //  by Connor Hodde

Brolucizumab is noninferior to aflibercept and requires less-frequent injections for patients with neovascular age-related macular degeneration (nAMD), according to results from two phase-3 trials. Earlier this month, Novartis announced that the U.S. Food and Drug Administration accepted the company's brolucizumab application for the treatment of nAMD. Reductions in central subfield thickness …

Category: News

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