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  • AboutUs_Normal-24 The EyeCRO Approach
    • About Us
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  • MiDrops MiDROPS™
  • InVivo Models
    • Allergic Conjunctivitis
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    • DL-AAA Retinal Leakage
    • Dry Eye Disease
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    • Experimental Autoimmune Uveitis
    • Geographic Atrophy
    • Inherited Retinal Degenerations
    • Ischemia Reperfusion Injury
    • Laser-induced Choroidal Neovascularization
    • Light Damaged
    • Mitochondrial Neuropathy
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    • Retinal Detachment
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    • STZ-induced Diabetic Retinopathy
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Preclinical Ophthalmic Contract Research

Aerie Pharmaceuticals Announces Potential Breakthroughs with New Preclinical Research

February 19, 2015 //  by stanselb

Aerie Pharmaceuticals, Inc. (AERI), a clinical-stage pharmaceutical company focused on the discovery, development and commercialization of first-in-class therapies for the treatment of patients with glaucoma and other diseases of the eye, announced today potentially breakthrough findings from new preclinical research.  The research found that RhopressaTM suppressed the activity of profibrotic proteins – TGF-beta 2 and CTGF – on human trabecular meshwork cells in an in vitro model.  In addition to RhopressaTM’s potential anti-fibrotic activity, another recent Aerie preclinical study indicates that RhopressaTM may increase the perfusion of the trabecular meshwork with aqueous humor.

Read the entire article here

Category: NewsTag: diseases of the eye, glaucoma, in vitro, perfusion, preclinical

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