No Link Found Between Genetic Risk Factors and Two Top Wet AMD Treatments

ByConnor Hodde

New findings from a landmark clinical trial show that although certain gene variants may predict whether a person is likely to develop age-related macular degeneration (AMD), these genes do not predict how patients will respond to Lucentis™ and Avastin™, the two medications most widely used to treat the “wet” form of AMD. This new data from the Comparison of AMD Treatment Trials (CATT), published online in Ophthalmology, the journal of the American Academy of Ophthalmology, found no significant association between four gene variants and outcomes that measured the patients’ responses to treatment.

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