Retinol-Binding Protein 4 Induces Inflammation in Human Endothelial Cells by a NADPH Oxidase- and Nuclear Factor Kappa B-dependent and Retinol-Independent Mechanism Krysten M. Farjoa,#, Rafal A. Farjob, Stacey Halseya, Gennadiy Moiseyeva and Jian-xing Maa aDepartment of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma beyecro LLC, Oklahoma City, Oklahoma ABSTRACT Serum retinol-binding protein…
A recent breakthrough from Hong Kong Polytechnic University uses tiger milk mushroom to prepare anti-tumor nanoparticles is bringing us one step closer. A natural compound found in mushrooms may hold the key to a new class of cancer drugs. In Tiger Milk mushrooms from Africa, Dr Wong Ka-hing, Associate Director of the Food Safety and…
Inhalable and thermo-responsive, fat-encased nanoparticles have been developed by researchers at the University of Sydney as possible treatment for lung cancer. The team has recently designed inhalable, targetable particles that can attack tumors but leave healthy cells undamaged, reducing the side effects of cancer treatment. The particles consist of a drug encased in a lipid…
The fast and targeted delivery of drugs to the focus of a disease could soon be made easier. Helmuth Möhwald and his colleagues from the Max Planck Institute of Colloids and Interfaces in Golm, Potsdam, have developed a simple technique for the production of drug containers which can be channelled to a selected target in…
Researchers at Johns Hopkins University (JHU) have created biodegradable, ultra tiny, nanosized particles that can easily slip through the body’s sticky and viscous mucus secretions to deliver a sustained-release medication cargo. The interdisciplinary team of researchers, led by Justin Hanes of the JHU Center for Nanomedicine, developed the nanoparticles so that they not only penetrate…
The American Health Assistance Foundation (AHAF), a nonprofit organization with a history of funding breakthrough research on age-related vision diseases, announced today that it has awarded 21 new grants totaling $2.1 million to scientists worldwide who are studying and macular degeneration. The two conditions are the leading causes of irreversible blindness in the world….
In a boost to localized disease treatment, research has yielded micro and nano-scale protein making machinery in capsule form, capable of manufacturing drugs inside the human body. The study was published in American Chemical Society’s (ACS) journal, Nano Letters. Proteins are the building blocks of drugs and integral to the human cell. Read more at…
Human-derived stem cells can spontaneously form the tissue that develops into the part of the eye that allows us to see, according to a study published by Cell Press in the 5th anniversary issue of the journal Cell Stem Cell. Transplantation of this 3D tissue in the future could help patients with visual impairments see…
According to the 2012 update of the “Vision Problems in the U.S.” report, a study released today by Prevent Blindness America and the National Eye Institute, the number of those ages 40 and older with vision impairment and blindness has increased 23 percent since the year 2000. In addition, a preliminary update to the 2007…
Conventional cancer treatments are accompanied by a host of side effects such as nausea and vomiting. The intensity of the side effects is many a time so acute that it poses a deterrent to further treatment. The reason behind the side effects is that existing cancer treatment methods do not address just the cancerous cells,…