Is Treat-and-Extend Truly Effective for Diabetic Macular Edema?

“Anti-vascular endothelial growth factor (anti-VEGF) medications have a proven track record in treating diabetic macular edema (DME). However, researchers continue to investigate whether these medications can be made more efficient and cost-effective.”

“Both the RETAIN^[1] and REACT^[2] studies showed that treat-and-extend regimens for ranibizumab were efficacious for DME. Further support was provided by the TREX-DME study, the first prospective, randomized controlled trial to evaluate ranibizumab 0.3 mg using a unique treat-and-extend algorithm.” (Read entire article here)