First successful transplant of retinas made from embryonic stem cells

ByConnor Hodde

For the first time, scientists have successfully transplanted light-detecting cells in the retina, grown from embryonic stem cells, into mice–a feat that could advance similar therapies using the artificial cells to treat degenerative eye diseases toward human trials. The animal transplant is a huge step for embryonic stem cell-based therapies, which have moved slowly to…

Transplanted Rod Precursor Cells Restore Vision in Experimental Mice

ByConnor Hodde

Studies in mouse models of night blindness have demonstrated that vision can be restored by transplanting rod precursor cells taken from mouse neonates directly into the retina of recipient animals. The University College London (UCL) Institute of Ophthalmology-led team showed that the transplanted rod cells made synaptic connections with the existing retinal circuitry, were light…