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  • AboutUs_Normal-24 The EyeCRO Approach
    • About Us
    • Careers
    • Location
    • Partners
  • MiDrops MiDROPS™
  • InVivo Models
    • Allergic Conjunctivitis
    • Corneal Sensitivity
    • Corneal Wound Healing
    • Diabetic Keratopathy
    • DL-AAA Retinal Leakage
    • Dry Eye Disease
    • Endotoxin induced Uveitis
    • Experimental Autoimmune Uveitis
    • Geographic Atrophy
    • Inherited Retinal Degenerations
    • Ischemia Reperfusion Injury
    • Laser-induced Choroidal Neovascularization
    • Light Damaged
    • Mitochondrial Neuropathy
    • Optic Nerve Crush
    • Oxygen Induced Retinopathy
    • Retinal Detachment
    • Retinal Vein Occlusion
    • STZ-induced Diabetic Retinopathy
    • VEGF-induced permeability
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Preclinical Ophthalmic Contract Research

Transplanted Rod Precursor Cells Restore Vision in Experimental Mice

May 7, 2012 //  by stanselb

Studies in mouse models of night blindness have demonstrated that vision can be restored by transplanting rod precursor cells taken from mouse neonates directly into the retina of recipient animals. The University College London (UCL) Institute of Ophthalmology-led team showed that the transplanted rod cells made synaptic connections with the existing retinal circuitry, were light responsive, and generated visual signals. The transplantation built on their previous photoreceptor transplantation research, and was optimized to increase the number of cells that integrated in the retina.

http://www.genengnews.com/gen-news-highlights/transplanted-rod-precursor-cells-restore-vision-in-experimental-mice/81246649/

Category: NewsTag: blindness, mouse models, mouse neonates, Ophthalmology, photoreceptor, retina, retinal circuitry, rod precursor cells, vision

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