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  • AboutUs_Normal-24 The EyeCRO Approach
    • About Us
    • Careers
    • Location
    • Partners
  • MiDrops MiDROPS™
  • InVivo Models
    • Allergic Conjunctivitis
    • Corneal Sensitivity
    • Corneal Wound Healing
    • Diabetic Keratopathy
    • DL-AAA Retinal Leakage
    • Dry Eye Disease
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    • Experimental Autoimmune Uveitis
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    • Laser-induced Choroidal Neovascularization
    • Light Damaged
    • Mitochondrial Neuropathy
    • Optic Nerve Crush
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    • Retinal Detachment
    • Retinal Vein Occlusion
    • STZ-induced Diabetic Retinopathy
    • VEGF-induced permeability
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Preclinical Ophthalmic Contract Research

photoreceptor cells

First Human Test of Optogenetics Could Restore Sight to the Blind

February 22, 2016 //  by stanselb

Before our brains build a visual image of our world, a chain of cells in our eyes must convert light into electrical signals that are processed in the brain. Photoreceptor cells in the retina represent the first link in this chain, and they are reactive to photons, or the fundamental particle of visible light. Retinitis pigmentosa causes these cells to degenerate, and patients with this …

Category: NewsTag: blind, degenerate, optogenetics, photoreceptor cells, restore sight, retina, retinal degeneration, retinitis pigmentosa, visible light

Scientists Successfully Apply Gene Therapy against Retinitis Pigmentosa

November 3, 2015 //  by stanselb

A collaboration between scientists in the UK and the USA has shown that gene therapy can give life-long protection to the light-sensitive photoreceptor cells responsible for colour vision in a mouse model of the most common inherited eye disorder.

  These findings are significant because they open up a new line of research to prevent nerve cell death in retinitis pigmentosa and age-related …

Category: NewsTag: Age-related macular degeneration, eye disorder, mouse model, Ophthalmology, photoreceptor cells, research, retina, retinitis pigmentosa, rhodopsin

New drug candidate is promising therapeutic option for angiogenic retinal diseases

October 20, 2015 //  by stanselb

A research team led by scientists at Beth Israel Deaconess Medical Center (BIDMC) and the University of New Mexico School of Medicine has identified a small molecule that treats animal models of aged macular degeneration (AMD) and retinopathy of prematurity (ROP) by preventing the overgrowth of blood vessels that are characteristic of these two retinal diseases.  The new findings, described in the …

Category: NewsTag: AMD, animal models, Diabetic retinopathy, eye drops, intravitreal injections, loss of vision, photoreceptor cells, retinal diseases, vascular endothelial growth factor, VEGF

Preserving photoreceptor cells following retinal injury: Inhibition of alternate complement pathway revealed

July 30, 2015 //  by stanselb

Retinal detachment can occur as a result of either blunt trauma or as a side effect of a variety of ophthalmic diseases, including diabetic retinopathy, ocular tumors, and age-related macular degeneration.  There is a significant increase in the immune system's 'alternative complement pathway' following retinal detachment, researchers report, adding that this pathway facilitated early …

Category: NewsTag: Age-related macular degeneration, Diabetic retinopathy, eye diseases, Ophthalmology, photoreceptor cells, Retinal detachment

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