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  • AboutUs_Normal-24 The EyeCRO Approach
    • About Us
    • Careers
    • Location
    • Partners
  • MiDrops MiDROPS™
  • InVivo Models
    • Allergic Conjunctivitis
    • Corneal Sensitivity
    • Corneal Wound Healing
    • Diabetic Keratopathy
    • DL-AAA Retinal Leakage
    • Dry Eye Disease
    • Endotoxin induced Uveitis
    • Experimental Autoimmune Uveitis
    • Geographic Atrophy
    • Inherited Retinal Degenerations
    • Ischemia Reperfusion Injury
    • Laser-induced Choroidal Neovascularization
    • Light Damaged
    • Mitochondrial Neuropathy
    • Optic Nerve Crush
    • Oxygen Induced Retinopathy
    • Retinal Detachment
    • Retinal Vein Occlusion
    • STZ-induced Diabetic Retinopathy
    • VEGF-induced permeability
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Preclinical Ophthalmic Contract Research

Retinal function, structure changes in proliferative diabetic retinopathy revealed

October 28, 2015 //  by stanselb

Patients with proliferative diabetic retinopathy (PDR) exhibit marked visual dysfunction and structural changes in both the inner and outer retinal layers, research findings indicate.

Retinal function was evaluated using a number of tests, including contrast sensitivity, frequency doubling perimetry (FDP) and photostress testing. And semiautomatically segmented spectral-domain optical coherence tomography scans were used to quantify thickness of retinal layers.  These findings “augment the current body of evidence for RPE degeneration in diabetes by demonstrating in vivo the presence of RPE–photoreceptor complex pathologic features in treated and untreated patients with PDR”, comment the researchers.

Read the entire article here.

Category: NewsTag: contrast sensitivity, Diabetic retinopathy, optical tomography, retina, retinal function, retinal pigment epithelium, RPE degeneration, visual dysfunction

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