Patients with proliferative diabetic retinopathy (PDR) exhibit marked visual dysfunction and structural changes in both the inner and outer retinal layers, research findings indicate.
Retinal function was evaluated using a number of tests, including contrast sensitivity, frequency doubling perimetry (FDP) and photostress testing. And semiautomatically segmented spectral-domain optical coherence tomography scans were used to quantify thickness of retinal layers. These findings “augment the current body of evidence for RPE degeneration in diabetes by demonstrating in vivo the presence of RPE–photoreceptor complex pathologic features in treated and untreated patients with PDR”, comment the researchers.
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