Retinal Remodeling And Metabolic Alterations in Human AMD

Age-related macular degeneration (AMD) is a progressive retinal degeneration resulting in central visual field loss, ultimately causing debilitating blindness.  While many genetic and environmental risk factors are known for AMD, we currently know less about the mechanisms mediating disease progression.  The goal of this article is to illustrate cell types impacted in AMD and demonstrate…

Flexible Adult Stem Cells, Right There in Your Eye

Researchers reporting in the January issue of Cell Stem Cell, a Cell Press publication, have identified adult stem cells of the central nervous system in a single layer of cells at the back of the eye. That cell layer, known as the retinal pigment epithelium (RPE), underlies and supports photoreceptors in the light-sensitive retina. Without…