Avalanche Biotechnologies, Inc. (AAVL) today announced the closing of the previously announced transaction with Annapurna Therapeutics. “The new management team is focused on applying our extensive clinical development expertise to advance the company’s gene therapy programs into the clinic. We intend on dosing our first patients for A1AT deficiency by the end of this year and for HAE in 2017 …
eye disease
Gut microbes linked to major autoimmune eye disease
One major cause of human blindness is autoimmune uveitis, which is triggered by the activation of T cells, but exactly how and where the T cells become activated in the first place has been a long-standing mystery. Autoimmune uveitis, which accounts for up to 15% of severe visual handicap in the Western world, affects the working-age population and significantly affects public health. Patients …
Study found possible association between drug and age-related macular degeneration
Daily aspirin use among seniors may double their risk of developing a particularly advanced form of age-related macular degeneration, a debilitating eye disease, a large new European study suggests. The possible link involves the so-called "wet" type of age-related macular degeneration (AMD), a significant cause of blindness in …