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Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4
“Retinol-binding protein 4 (RBP4) is a novel adipokine (adipose-derived cytokine) that is clinically associated with obesity, insulin resistance, type 2 diabetes (T2DM), and cardiovascular disease. In addition, patients with proliferative diabetic retinopathy (DR) have increased serum RBP4 levels compared to diabetic patients with mild or no retinopathy, which raises the possibility that RBP4 is somehow…
New Report from Prevent Blindness America Shows Sharp Increase in Eye Disease Prevalence
According to the 2012 update of the “Vision Problems in the U.S.” report, a study released today by Prevent Blindness America and the National Eye Institute, the number of those ages 40 and older with vision impairment and blindness has increased 23 percent since the year 2000. In addition, a preliminary update to the 2007…
Groundbreaking Research Published in Collaboration with the National Eye Institute
We are thrilled to announce the publication of our latest research in eLife. This milestone represents an inspiring collaboration between EyeCRO and the esteemed laboratory of Dr. Anand Swaroop at the National Eye Institute. Our partnership exemplifies how teamwork and shared vision can advance the frontiers of science and medicine, particularly in the development of…
eyecro and NeuMedics announce collaboration to utilize MiDROPS™ technology for the development of NM108
Oklahoma City, OK, and Seattle, WA; (May 4, 2015) – eyecro LLC and NeuMedics Inc., today announced the formation of a collaboration to facilitate development of NM108, a first-in-class small molecule to treat a number of ophthalmic disorders that lead to blindness, including Diabetic Retinopathy. The collaboration grants NeuMedics full access to the MiDROPS™ formulation…
FLUID Study Rethinks Treat-and-Extend Protocols in Neovascular AMD
“For patients with neovascular age-related macular degeneration (nAMD), a major cause of visual impairment worldwide,[1] the advent of anti–vascular endothelial growth factor (VEGF) intravitreal injections has been an undeniable breakthrough. Anti-VEGF therapy allows for greater control of the exudative process, which can dramatically improve outcomes compared with observation alone.” “Achieving and maintaining a dry macula in the…
Drusen Characteristics Linked With AMD Risk in Fellow Eyes
“NEW YORK (Reuters Health) – In patients with unilateral neovascular age-related macular degeneration (AMD), certain drusen features are associated with conversion to neovascular AMD in the fellow eye, according to a secondary analysis of data from a clinical trial. Dr. Joelle A. Hallak of the University of Illinois at Chicago and colleagues used machine learning…

