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  • AboutUs_Normal-24 The EyeCRO Approach
    • About Us
    • Careers
    • Location
    • Partners
  • MiDrops MiDROPS™
  • InVivo Models
    • Allergic Conjunctivitis
    • Corneal Sensitivity
    • Corneal Wound Healing
    • Diabetic Keratopathy
    • DL-AAA Retinal Leakage
    • Dry Eye Disease
    • Endotoxin induced Uveitis
    • Experimental Autoimmune Uveitis
    • Geographic Atrophy
    • Inherited Retinal Degenerations
    • Ischemia Reperfusion Injury
    • Laser-induced Choroidal Neovascularization
    • Light Damaged
    • Mitochondrial Neuropathy
    • Optic Nerve Crush
    • Oxygen Induced Retinopathy
    • Retinal Detachment
    • Retinal Vein Occlusion
    • STZ-induced Diabetic Retinopathy
    • VEGF-induced permeability
  • InVitro Capabilities
    • A2E Quantification
    • Bioanalytical Detection
    • Biochemistry
    • Histology
    • Ophthalmic Imaging and Physiology
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Preclinical Ophthalmic Contract Research

photoreceptors

RetroSense Granted Orphan Drug Designation for Retinitis Pigmentosa

November 12, 2014 //  by stanselb

RetroSense Therapeutics, LLC, a privately-held biopharmaceutical company, announced today that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug designation for the Company’s lead product RST-001 for the treatment of retinitis pigmentosa (RP). Retinitis pigmentosa is a genetic condition which leads to the progressive degeneration of rod and cone photoreceptors (cells found in the …

Category: NewsTag: degeneration, optogenetics, photoreceptors, retina, retinitis pigmentosa, vision loss

Rosemary Compound Shown To Help Fight Macular Degeneration In Mouse Model

December 7, 2012 //  by stanselb

A new study led by the Sanford-Burnham Medical Research Institute reports that carnosic acid, found in the herb rosemary, actually promotes eye health. Led by Dr. Stuart A. Lipton, the team found that carnosic acid protects the retina from degeneration and toxicity in cell culture and in rodent models of light-induced retinal damage. This suggests that carnosic acid may have clinical …

Category: NewsTag: Age-related macular degeneration, carnosic acid, cell culture, degeneration, electroretinogram, light-induced retinal damage, oxidative stress, photoreceptors, retina, retinitis pigmentosa, rodent models

Scientists See New Hope for Restoring Vision With Stem Cell Help

July 5, 2012 //  by stanselb

Human-derived stem cells can spontaneously form the tissue that develops into the part of the eye that allows us to see, according to a study published by Cell Press in the 5th anniversary issue of the journal Cell Stem Cell. Transplantation of this 3D tissue in the future could help patients with visual impairments see clearly. During development, light-sensitive tissue lining the back of the …

Category: NewsTag: hESC, optic cup, photoreceptors, retina, stem cells

Flexible Adult Stem Cells, Right There in Your Eye

January 20, 2012 //  by stanselb

Researchers reporting in the January issue of Cell Stem Cell, a Cell Press publication, have identified adult stem cells of the central nervous system in a single layer of cells at the back of the eye. That cell layer, known as the retinal pigment epithelium (RPE), underlies and supports photoreceptors in the light-sensitive retina. Without it, photoreceptors and vision are lost. "You can get …

Category: NewsTag: eye, photoreceptors, retina, retinal pigment epithelium, RPE, Stem Cell, vision

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