By combining data on optometry patient’s eyes with advanced computational methods, Indiana University researchers have created a virtual tissue model of diabetes in the eye. The results, reported in the journal PLOS Computational Biology, show precisely how a small protein that can both damage or grow blood vessels in the eye causes vision loss and…
Diabetic retinopathy — an eye condition that affects people with diabetes — is the fastest growing cause of blindness, with nearly 415 million diabetic patients at risk worldwide. The disease can be treated if detected early, but if not, it can lead to irreversible blindness. A few years ago, a Google research team began studying…
Experimental and clinical data suggest that pro-angiogenic, pro-inflammatory and mitogenic cytokine leptin can be implicated in ocular neovascularization and the other eye pathologies. At least in part, leptin action appears to be mediated through functional interplay with vascular endothelial growth factor (VEGF). The effects of VEGF on leptin expression were assessed in ocular endothelial cell…
Robert MacLaren, Professor of Ophthalmology. assisted by Dr Thomas Edwards, Nuffield Medical Fellow, used the remotely controlled robot to lift a membrane 100th of a millimetre thick from the retina at the back of the right eye of the Revd Dr William Beaver, 70, an Associate Priest at St Mary the Virgin, Iffley, Oxford. He…
Global pharmaceutical company Allergan (NYSE:AGN) may have just revealed its plans for the future. On Aug. 11, the company announced its plan to acquire ForSight Vision5, a privately held biotech. Allergan will pay $95 million up front and will also pay a milestone payment next year if ForSight’s innovative glaucoma treatment device makes it through the…
WATERTOWN, Mass., July 14, 2016 (GLOBE NEWSWIRE) — pSivida Corp. (NASDAQ:PSDV) (ASX:PVA), a leader in the development of sustained release drug delivery products primarily for eye diseases, announced that the results from an investigator-sponsored Phase 2 study of pSivida’s Medidur showed no recurrence of uveitis in 11 eyes treated with Medidur during the two years…
A trio of eyeglasses using revolutionary prism techniques could open up a whole new field of view for patients with hemianopia. The three designs – yoked prisms in a carrier lens, a bi-part double Fresnel prism, and the mirror-based periscopic prisms – were showcased in the journal Optometry and Vision Science. Lead researcher and Harvard…
Pathologic changes of the retina caused by diabetes is the leading cause of blindness in working adults. Diabetic retinopathy has no known cure, treatment options are inadequate, and prevention strategies offer limited protection. In the first of its kind, a report in The American Journal of Pathology describes a potential new intraocular treatment based on…
Age-related macular degeneration (AMD) is a progressive retinal degeneration resulting in central visual field loss, ultimately causing debilitating blindness. While many genetic and environmental risk factors are known for AMD, we currently know less about the mechanisms mediating disease progression. The goal of this article is to illustrate cell types impacted in AMD and demonstrate…