Non-GLP Safety

 

Ophthalmic Safety and Tolerability Studies

Animals:

Rat, Rabbit, micro-pig (Coming soon!)

Identification of NOAEL by clinical ophthalmic examination including evaluation of:

  • Aqueous Flare
  • Chemosis
  • Choroidal/Retinal Inflammation
  • Discomfort
  • ERG Analyses
  • Hyperemia
  • H&E Histology
  • Intra Ocular Pressure
  • Lens Cataract
  • Pupil Response
  • Retinal Detachment
  • Retinal Hemorrhage
  • Retinoid Profiling
  • Swelling
  • Vascularization
  • Vitreous Cells
  • Vitreous Hemorrhage

 

Preclinical Ophthalmic Contract Research